IIT Kanpur

Education / Work History

  • Ph.D. Scholar, IIT Kanpur (2013-present)
  • M.Sc, University of Delhi (2008-2010)
  • B.Sc, Deshbandhu College Delhi (2008)

Research Topic / Interest

My main interest is currently:

  • Thermal Lens Microscopy

Publications

These include only those published in our lab.

  1. Deciphering Micro-Polarity inside the Endoplasmic Reticulum Using a Two-Photon Active Solvatofluorochromic Probe. K. Pal, I. Samanta, R. Kumar Gupta, D. Goswami, and A. Lal Koner, Chemical Communications 54(75), 10590–10593 (2018) [PDF] [BibTeX]
     BibTeX: @article{palDecipheringMicropolarityEndoplasmic2018,
      langid = {english},
      title = {Deciphering Micro-Polarity inside the Endoplasmic Reticulum Using a Two-Photon Active Solvatofluorochromic Probe},
      volume = {54},
      url = {https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc03962c},
      doi = {10/gf5mqx},
      number = {75},
      journaltitle = {Chemical Communications},
      urldate = {2019-08-01},
      date = {2018},
      pages = {10590-10593},
      author = {Pal, Kaushik and Samanta, Indranil and Kumar Gupta, Rahul and Goswami, Debabrata and Lal Koner, Apurba}
    }
    
  2. White Light Induced E/Z-Photoisomerization of Diphenylamine-Tethered Fluorescent Stilbene Derivatives: Synthesis, Photophysical, and Electrochemical Investigation. S. Mishra, P. Awasthi, J. Singh, R. K. Gupta, V. Singh, R. Kant, R. Jeet, D. Goswami, and A. Goel, The Journal of Organic Chemistry 83(7), 3669–3678 (2018) [Abstract] [PDF] [BibTeX]

    Abstract: A facile synthesis and detailed photophysical investigation of E/Z-isomerization of fluorescent diphenylamine tethered stilbene derivatives (DPASs) under white light exposure have been carried out to understand the effect on fluorescence, electrochemical properties, and photostability under various activation/deactivation pathways. In solution state, in the dark, the E-isomer of DPASs (6a−d) exhibited high fluorescence quantum yields (Φfl ≈ 53% to 60% in DMSO). However, on white light exposure, 1H NMR and HPLC studies revealed that pure E-isomer of the DPAS 6a (∼9.5 mM) started converting into its Z-form by photoisomerization until it reaches to nearly equilibrium. At low concentrations (∼10 μM), the absorption band of the pure Eisomer in the range of 350−450 nm gradually decreased to adopt Z-conformation 6a′ until a photostationary state was reached. The structure of the E-isomer 6a was unequivocally confirmed by X-ray diffraction analysis. The synthesized DPAS compounds 6a−d possessed positive solvatochromic properties, two photon absorption properties, and good thermal stability. The electrochemical investigations using DPASs showed reversible oxidation resulting in formation of a stable radical cation. Owing to useful photophysical, electrochemical and thermal properties, these DPAS derivatives are suitable for their application in biomedical imaging as well as in fabrication of electroluminescent materials.

     BibTeX: @article{mishraWhiteLightInduced2018,
      langid = {english},
      title = {White {{Light Induced E}}/{{Z}}-{{Photoisomerization}} of {{Diphenylamine}}-{{Tethered Fluorescent Stilbene Derivatives}}: {{Synthesis}}, {{Photophysical}}, and {{Electrochemical Investigation}}},
      volume = {83},
      issn = {0022-3263, 1520-6904},
      url = {http://pubs.acs.org/doi/10.1021/acs.joc.8b00033},
      doi = {10/gc6tzq},
      shorttitle = {White {{Light Induced E}}/{{Z}}-{{Photoisomerization}} of {{Diphenylamine}}-{{Tethered Fluorescent Stilbene Derivatives}}},
      number = {7},
      journaltitle = {The Journal of Organic Chemistry},
      shortjournal = {J. Org. Chem.},
      urldate = {2019-08-01},
      date = {2018-04-06},
      pages = {3669-3678},
      author = {Mishra, Shachi and Awasthi, Pallavi and Singh, Jagriti and Gupta, Rahul Kumar and Singh, Vikram and Kant, Ruchir and Jeet, Ram and Goswami, Debabrata and Goel, Atul}
    }
    
  3. Deciphering Micro-Polarity inside the Endoplasmic Reticulum Using a Two-Photon Active Solvatofluorochromic Probe. K. Pal, I. Samanta, R. Kumar Gupta, D. Goswami, and A. Lal Koner, Chemical Communications 54(75), 10590–10593 (2018) [PDF] [BibTeX]
     BibTeX: @article{palDecipheringMicropolarityEndoplasmic2019,
      langid = {english},
      title = {Deciphering Micro-Polarity inside the Endoplasmic Reticulum Using a Two-Photon Active Solvatofluorochromic Probe},
      volume = {54},
      url = {https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc03962c},
      doi = {10/gf5mqx},
      number = {75},
      journaltitle = {Chemical Communications},
      urldate = {2019-08-01},
      date = {2018},
      pages = {10590-10593},
      author = {Pal, Kaushik and Samanta, Indranil and Kumar Gupta, Rahul and Goswami, Debabrata and Lal Koner, Apurba}
    }
    
  4. White Light Induced E/Z-Photoisomerization of Diphenylamine-Tethered Fluorescent Stilbene Derivatives: Synthesis, Photophysical, and Electrochemical Investigation. S. Mishra, P. Awasthi, J. Singh, R. K. Gupta, V. Singh, R. Kant, R. Jeet, D. Goswami, and A. Goel, J. Org. Chem. 83(7), 3669–3678 (2018) [Abstract] [PDF] [BibTeX]

    Abstract: A facile synthesis and detailed photophysical investigation of E/Z-isomerization of fluorescent diphenylamine tethered stilbene derivatives (DPASs) under white light exposure have been carried out to understand the effect on fluorescence, electrochemical properties, and photostability under various activation/deactivation pathways. In solution state, in the dark, the E-isomer of DPASs (6a−d) exhibited high fluorescence quantum yields (Φfl ≈ 53% to 60% in DMSO). However, on white light exposure, 1H NMR and HPLC studies revealed that pure E-isomer of the DPAS 6a (∼9.5 mM) started converting into its Z-form by photoisomerization until it reaches to nearly equilibrium. At low concentrations (∼10 μM), the absorption band of the pure Eisomer in the range of 350−450 nm gradually decreased to adopt Z-conformation 6a′ until a photostationary state was reached. The structure of the E-isomer 6a was unequivocally confirmed by X-ray diffraction analysis. The synthesized DPAS compounds 6a−d possessed positive solvatochromic properties, two photon absorption properties, and good thermal stability. The electrochemical investigations using DPASs showed reversible oxidation resulting in formation of a stable radical cation. Owing to useful photophysical, electrochemical and thermal properties, these DPAS derivatives are suitable for their application in biomedical imaging as well as in fabrication of electroluminescent materials.

     BibTeX: @article{mishraWhiteLightInduced2019,
      langid = {english},
      title = {White {{Light Induced E}}/{{Z}}-{{Photoisomerization}} of {{Diphenylamine}}-{{Tethered Fluorescent Stilbene Derivatives}}: {{Synthesis}}, {{Photophysical}}, and {{Electrochemical Investigation}}},
      volume = {83},
      issn = {0022-3263, 1520-6904},
      url = {http://pubs.acs.org/doi/10.1021/acs.joc.8b00033},
      doi = {10/gc6tzq},
      shorttitle = {White {{Light Induced E}}/{{Z}}-{{Photoisomerization}} of {{Diphenylamine}}-{{Tethered Fluorescent Stilbene Derivatives}}},
      number = {7},
      journaltitle = {J. Org. Chem.},
      urldate = {2019-08-01},
      date = {2018-04-06},
      pages = {3669-3678},
      author = {Mishra, Shachi and Awasthi, Pallavi and Singh, Jagriti and Gupta, Rahul Kumar and Singh, Vikram and Kant, Ruchir and Jeet, Ram and Goswami, Debabrata and Goel, Atul}
    }